Pacientes com artrite reumatoide atendidos na farmácia ambulatorial do Hospital Universitário Walter Cântido (HUWC): características e medicamentos utilizados

Abstract

Rheumatoid arthritis is an inflammatory disease that compromises the extremities of joints, including fingers, knees, elbows, shoulders and ankles. Like other autoimmune diseases, environmental and genetic factors contribute to the breakdown of the tolerance of autoantigens. The prevalence of RA is 0.5% to 1% of the population, being the majority of cases in adult female patients between the third and fifth decades of life. This study aimed to characterize patients with rheumatoid arthritis treated at the HUWC outpatient pharmacy. Data from 889 patients were analyzed. The majority of the patients were in the age range of 40 to 69 years (77.17%), the majority being female (91.73%). In all, 889 patients consumed a total of 1385 medications. Most used two drugs, 451 (50.73%). The drugs dispensed represented 17 pharmaceutical presentations. Of the 17 pharmaceutical presentations, six were oral (6.35%), six subcutaneous (6.35%) and five intravenous (5.30%). The most used drugs were leflunomide (35.31%) and methotrexate (33.79%). From the development of the present study, it was possible to observe that the majority of the patients with RA were female, aged between 40 and 59 years, who used 2 medicines dispensed by CEAF, most of the medicines being dispensed the Medicamentos Modificadores of Synthetic Diseases (MMCD). Although the anti-TNF drugs were not the most dispensed drugs, they were in second place