Estudo das lesões de trato gastrointestinal alto de pacientes vivendo com HIV, no Ceará, em 2017

Abstract

HIV infection is still a topic of great concern in public health. Despite the better access and universal use of antiretroviral drugs, late diagnosis and oportunistic diseases are still frequent, and this presentation has been globally called advanced disease. Gastrointestinal system is among the main sites involved in disease in people living with HIV, hosting manifestations of oportunistic diseases and other pathologic alterations not related to immunosupression. The objective of the presente study is to describe the endoscopic findings of a sample of patients living with HIV, followed in a regional reference hospital for infectious diseases in 2017, considering intensity of immunossupression, aiming to facilitate the decision making process for phisicians and to guide local public health iniciatives for this specific population.A revision of 113 files of patients followed in Hospital são José de Doenças infecciosas, in the state of Ceará, and who had an Upper endoscopy performed with biopsy for histopathological evaluation. Most of the patients were male (65%), which is consistent with national data, and mean age was 42 years, with no difference between genres. The mean CD4 count was 325 cels/mm3, ad the symptom reported to indicate the exam was dispepsia. Among the comorbidities, tuberculosis was the most prevalent, followed by neurotoxoplasmosis. In histopathologic analysis, inflammatory findings were the most present in all parts of upper gastrointestinal tract, followed by gastric atrophy and metaplastic mucosa, and ulcers. H. pylori testing was positive in 60,2% of cases, Candida esophagitis was found in 11,6% and CMV disease, in 6,5% of patients.