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http://repositorio.ufc.br/handle/riufc/40486
Tipo: | Artigo de Periódico |
Título : | Evaluation of the antifungal effect vitis vinifera extracton Candida albicans |
Autor : | Gadelha, Leandro Maciel Uchoa Valada, Lídia Audrey Rocha Fiallos, Nicole de Mello Peralt, Sônia Luque Mendonça, Keniesd Sampaio Lotif, Mara Assef Leitão Bezerra, Gilvan Lima Aguia, Márcio Glauber Lopes de Diógenes, Érika Sabóia Guerra Rodrigues Neto, Edilson Martins Asevedo, George Otávio Fiallo, Ana Cristina de Mello |
Palabras clave : | Extrato de Sementes de Uva;Grape Seed Extract;Estomatite;Stomatitis;Candida albicans;Prótese Dentária;Dental Prosthesis |
Fecha de publicación : | mar-2018 |
Editorial : | Journal of Young Pharmaciation |
Citación : | GADELHA, Leandro Maciel Uchoa et al. Evaluation of the antifungal effect Vitis vinifera extract on Candida albicans. Journal of Young Pharmacists, v. 10, n. 2, p. 164-168, mar. 2018. |
Abstract: | Objective: This research analyzed in vitro the antifungal activity of the solution composed by grapes seed extract Vitis vinifera (Doctor’s A-Z®) against Candida albicans (ATCC 20231) species aiming to determine the minimum inhibitory concentration (MIC) and minimum fungicide concentration (MFC). Methods: To that, were used micro dilution boards of 96 wells where the strain of Candida. Was tested the diluted solutions in distilled water on the concentrations 0.20 g/mL, 0.30 g/mL and 0.40 g/mL. As growing control were used growing fungous, to test the viability of the strains. As positive control, was used nystatin (commercial suspension 100,000 UI/mL) and as sterility control of growing way. The tests were conducted in triplicate and the data obtained were analyzed through the exam Kruskal-Wallis, with significance level of 95% (p<0.05). Results: The results indicated that all the samples were sensible to the analyzed extract and the CIM was obtained with the solution of 0.30 g/mL (30%). However, wasn’t observed a fungicid effect (MFC) on the tested concentrations. Conclusion: We conclude that the grapes seed extract can be an alternative against the gender Candida, however are necessary larger studies to prove their ant fungous action. |
URI : | http://www.repositorio.ufc.br/handle/riufc/40486 |
ISSN : | 0975-1483 Online - 0975-1505 |
Aparece en las colecciones: | DFAR - Artigos publicados em revistas científicas |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
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2018_art_lmugadelha.pdf | 159,09 kB | Adobe PDF | Visualizar/Abrir |
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