Estudo Químico da raiz de Jatropha mollissima (Pohl) Baill; identificação de compostos fenólicos em quatro espécies do gênero Anthurium através de Cromatografia Líquida acoplada à Espectrometria de Massas.

Abstract

This work aimed to study the chemical from the root of Jatropha mollissima (Euphorbiaceae), a plant native to northeastern Brazil. In this study we used chromatographic techniques in an attempt to isolate the chemical constituents of hexane and ethanol extracts of the root. Chromatographic treatment of extract allowed the isolation of a long aliphatic chain alcohol called triacontanol, a mixture of the steroids B-sitosterol and stigmasterol and a terpene latirano skeleton called jatrogrossidiona. Also in this work, we investigated the composition of phenolic compounds present in methanol extracts of leaves of four species of the genus Anthurium using HPLC - MS in which it was possible to identify eight phenolic compounds: 6- C- arabinosyl -8- C- glycosyl - apigenin in the leaves of A. lindmanianum; 8-O-ramnosyl-( 1-3)-C-glycosyl - acacetin and 7-O-[6-O-acetylglicosyl(1-2)]ramnosyl-( 1-6 )-glycosyl - acacetin in the leaves of A. andraeanum, 5- caffeoylquinic acid, vitexin, isovitexin and Orientin in the leaves of A. bonplandii and 6- O-ramnosyl-( 1-3)-C-glycosyl-acacetin in the leaves of A. plowmanii. The results for the inhibition of acetylcholinesterase enzyme showed that only the hexane extract of J. mollissima and methanol extract from the leaves of A. andraeanum showed anticholinesterase activity.