Efeitos da ingestão aguda do suco de acerola em um teste incremental até a exaustão

Abstract

Acerola (Malpighia ermaginata) is a tropical fruit rich in carotenoids, phenolics, flavonoids and anthocyanins, used in several studies for its pharmacological properties, especially its antioxidant and anti-inflammatory activities, through in vitro and in vivo approaches. Biocompounds such as flavonoids and anthocyanins, present in acerola, have immunomodulatory effects and suppressive effects on reactive oxygen species (Eros) and nitrogen (ERN). The practice of strenuous exercises increases the release of these substances, along with a transient increase in circulating leukocytes. Thus, our aim with this study was to investigate whether the intake of a single dose of acerola juice pre exhaustive exercise would promote changes in performance, biochemical responses and acute immune response. Twelve trained adult men participated in the randomized, crossover, and double-blind study, where they consumed a single dose of acerola juice (ACE) or a control drink (CON) two hours before the incremental treadmill test until exhaustion. The total time of the test, the distance traveled and the lipid peroxidation of the participants did not differ between groups (p ≥ 0.05). But an increase for serum albumin, decrease of serum uric acid and a protective effect to increase levels of CK, LDH, TGO and TGP were observed in the ACE group. In the differential count of neutrophils, lymphocytes, monocytes, eosinophils, band cells and basophils there was no significant effect (p ≥ 0.05) with the intake of ACE or CON drink. But a decrease with practical effect was observed for monocyte count in the CON group. Thus, possibly due to the protective effect of its biocomposites and the synergy of its phytonutrients, we observed an effect of acerola juice against increased acute tissue damage for exercise and decreased monocytes after strenuous exercise.