Associação entre fadiga e dinamometria manual em pacientes com câncer hematológico internados em um hospital

Abstract

Introduction: Onco-hematological individuals undergoing chemotherapy may present fatigue and sarcopenia, which may cause functional and quality of life impairments. Main Objective: To verify the relationship between reported fatigue and peripheral muscle strength (MPF) in oncohematological patients. Methods: Study with quantitative, observational cross-sectional approach in individuals with onco-hematological diseases, between August 2019 and October 2021. A questionnaire was applied with general data and information on hematological values. The MPF was evaluated by measuring palmar grip strength. Fatigue assessment was verified by the Piper-revised Fatigue Scale. It was considered statistically significant when the p value was less than or equal to 0.05. Results: Sample of 54 individuals. Main pathology: acute myeloid leukemia (n=20, 37%); main treatment: chemotherapy (n=45, 83.3%); presence of fatigue: 16 (29.6%). There was a statistically significant reduction in the predicted FMP ratio x obtained, 36.8% - dominant arm (p=0.000) and 27.5% - non-dominant hand (p=0.000). In the correlation between age, BMI, time of diagnosis of the disease, hematological values and MPF, there was a correlation only between muscle strength obtained (dominant and non-dominant hand) (R=0.862; P= 0.000), between the time of diagnosis with hematological values and between neutrophils (R=0.483; P=0.000) and hemoglobin (R=0.445; P=0.001). In the association between the presence of fatigue with the variables of MPF, age, BMI and hematological values, no association was observed Conclusion: There was no association between fatigue and muscle strength, hematological values, age or BMI.