Please use this identifier to cite or link to this item:
http://repositorio.ufc.br/handle/riufc/10343
Type: | Artigo de Periódico |
Title: | Differences among children, adolescents and adults with severe leptospirosis : a comparative analysis |
Authors: | Daher, Elizabeth de Francesco Vieira, A. P. F. Jacinto, C. N. Lima, R. S. A. Girão, M. M. V. Fernandes, A. T. B. M. P. Neto, R. J. Silva Junior, Geraldo Bezerra |
Keywords: | Leptospirose;Lesão Renal Aguda;Criança |
Issue Date: | May-2014 |
Citation: | DAHER, E. F. et al. Differences among children, adolescents and adults with severe leptospirosis : a comparative analysis. Indian Journal of Nephrology, v. 24, n. 3, p. 166-170, maio/jun. 2014. |
Abstract: | Leptospirosis is a zoonosis of global importance caused by Leptospira interrogans. The aim of this study was to compare the data between children, adolescents and adults with leptospirosis. This is a retrospective study including a total of 373 consecutive patients with leptospirosis, admitted to tertiary hospitals in Northeast of Brazil, from May 1985 to August 2010. The patients were divided into two groups (age ≤21 years and >21 years). The adults were 304 (81.5%) of the population, with a mean ge of 41 ± 13 (range 22‑84) years. The pediatric group was 16 ± 3 (range 9‑21) years. Signs and symptoms where similar between the groups, excepting arrhythmia, which was more frequent in adults and vomiting, more common in children (16% vs. 0%, P = 0.04 and 65% vs. 79%, P = 0.02), respectively. Adult group presented with higher serum urea (137 vs. 97 mg/dl, P = 0.002) and creatinine (4.3 vs. 3.0 mg/dl, P = 0.007). Acute kidney injury (AKI) was observed in 80%, mainly in adults (83% vs. 70% P < 0.005). Adults required renal replacement therapy more frequently than children (38% vs. 11%, P < 0.0001). Mortality was higher in adults (14.8% vs. 2.8%, P = 0.005) and in adults with AKI (93% vs. 7%, P < 0.05). There are important differences between the adults and children with leptospirosis. AKI was more frequent in adults and it was associated with increased mortality. |
URI: | http://www.repositorio.ufc.br/handle/riufc/10343 |
ISSN: | 0971-4065 Impresso 1998-3662 On line |
Appears in Collections: | DMC - Artigos publicados em revistas científicas |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
2014_art_gbsilvajunior.pdf | 471,89 kB | Adobe PDF | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.