Qualidade de vida em pacientes em hemodiálise com neoplasia : associação com o complexo desnutrição-inflamação

Abstract

Introduction: The aim of this study was to compare levels of depression, quality of life and sleep quality between hemodialysis patients with or without cancer and to analyze associations with malnutrition-inflammation-atherosclerosis (MIA) syndrome. Methods: In this cross-sectional study 40 cancer patients under hemodialysis and 44 patients under hemodialysis without cancer who served as the control group were included. Participants underwent structured interviews to investigate depression, quality of life, sleep quality and restless legs syndrome. Results: Hemodialysis patients with cancer had a greater depression score (16.5±4.8 vs. 10.8±5.2, p<0.001), and Patients had similar physical and mental composite quality of life scores. Patients under hemodialysis with cancer had poorer quality of sleep (mean score 8.8±3.5 vs. 6.4±4.1, p=0.011) and a higher prevalence of restless leg syndrome (55.9% vs. 25.7%, p=0.011). Hemodialysis patients with cancer had a mean MIA Syndrome greater than those without cancer (15.1±5.7 vs. 10.0±4.7, p<0.001). Conclusion: Cancer patients under hemodialysis present a higher prevalence of depression, poor quality of life, poor quality of sleep disorders and increased frequency of malnutrition-inflammation syndrome compared to their non-cancer counterparts.