Please use this identifier to cite or link to this item: http://repositorio.ufc.br/handle/riufc/8390
Type: Artigo de Periódico
Title: Clinical and serological evolution in chronic Chagas disease patients in a 4-year pharmacotherapy follow-up : a preliminary study
Authors: Andrade, Mônica Coelho
Oliveira, Maria de Fátima
Nagao-Dias, Aparecida Tiemi
Coêlho, Ivo Castelo Branco
Bezerra, Fernando Schemelzer Moraes
Freitas, Erlane Chaves
Coelho, Helena Lutéscia Luna
Cândido, Darlan da Silva
Keywords: Doença de Chagas;Quimioterapia
Issue Date: Nov-2013
Publisher: Revista da Sociedade Brasileira de Medicina Tropical
Citation: ANDRADE, M. C. et al. Clinical and serological evolution in chronic Chagas disease patients in a 4-year pharmacotherapy follow-up : a preliminary study. Revista da Sociedade Brasileira de Medicina Tropical, v. 46, n 6, p. 776-778, nov./dec., 2013.
Abstract: Introduction: The role of trypanocidal therapy in the chronic phase of Chagas disease remains controversial. Methods: A total of 13 patients with chronic Chagas disease were treated with benznidazole (5mg/kg/day/60 days) and surveyed via antibody measurement and conventional electrocardiogram over the course of 4 years. Results: The antibody titers were signifi cantly reduced after 4 years (p<0.05). Most of the patients showed maintenance of the initial clinical picture (electrocardiographic), with the exception of 4 cases. Conclusions: Although trypanocidal therapy in the chronic phase of Chagas disease was of limited effectiveness, we believe that it is benefi cial in treating these patients.
URI: http://www.repositorio.ufc.br/handle/riufc/8390
Appears in Collections:DPML - Artigos publicados em revista científica

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