Desempenho físico em pacientes com doença de Parkinson: análise de fatores sociodemográficos, clínicos e componentes da sarcopenia

Abstract

This cross-sectional study evaluated 129 PD patients in Fortaleza, Brazil, examining associations between physical performance (SPPB), sarcopenia components and clinical factors. Mean age was 66±11 years, with 39% showing low physical performance (SPPB≤8). Key findings:

Older age (68±11 vs 64±10 years, p=0.016)

Physical inactivity (24% vs 53% active, p=0.002)

Higher MDS-UPDRS part 3 (51±15 vs 39±13, p<0.001)

Elevated SARC-F (5.88±2.53 vs 2.92±2.31, p<0.001) were associated with worse performance. Regression models identified SARC-F (OR:3.97) and PIGD (OR:1.53) as independent predictors. The SARC-F≥4 + PIGD combination best discriminated performance levels (AIC=135.5).