Prevalência de Candida em Hemoculturas em pacientes de um Hospital Universitário no Brasil

Abstract

Candidemia is a serious public health problem and is associated with high morbidity and mortality rates. This study aimed to determine the prevalence of Candida species isolated from inpatients with candidemia at a teaching hospital in Brazil; characterize patients; correlate the risk factors and investigate the use of antibiotics. Medical records of 54 hospitalized patients from October 2013 to July 2015 were evaluated. The species identification was performed by automated system Vitek ® 2. In this period there were 19,962 hospitalizations, observing a frequency of 2.7 cases per 1,000 admissions. The prevalent species were Candida albicans (29.6%), C. tropicalis (29.6%), and C. parapsilosis (29.6%). Neonatal sepsis was the clinical condition more related to candidemia. The highest incidence of Candida species was observed in patients undergoing invasive procedures. All subjects studied were submitted to prolonged antibiotic therapy. The greatest diversity of Candida species was isolated from the Intensive Care Unit (ICU) and adult wards. The mortality rate found was 51.0%, of which 78.0% were ICU patients. These results reinforce the need to follow the clinical course of hospitalized patients for Candida infection through epidemiological surveillance in order to contribute to the action plan