Adesão terapêutica na insuficiência cardíaca e perfil clínico de descompensação

Abstract

Background: In patients with heart failure (HF), therapeutic adherence is important in the mortality of patients. There is a relationship between mortality and clinical profiles of hospitalization in heart failure decompensated. Objective: To evaluate the relationship between the level of adherence by the Morisky-Green method (TMG) and the Clinical Profile of hospitalization and the correspondence of the adherence level with sociodemographic variables. Methods: Analytical cross-sectional observational study including patients with a clinical picture of HF admitted to the period from January 2015 to June 2018. They were divided into clinical hospitalization profiles based on the characteristics of arrival at the hospital and assessment of adherence to treatment with TMG. The data Categorical data were analyzed using Fisher's exact tests. Additionally, logistic regression model multinomial was designed to plot the independent risk factors for the analyzed outcomes. Results: The sample was completed with 306 patients. In the clinical-cardiological characterization of the patients, we found higher mortality in patients in NYHA functional class IV (83.3%, p = 0.040), Cold Profile and Congestive (50.0%, p = 0.002) and Echocardiogram with Ejection Fraction less than 40% (62.5%, p = 0.017). We observed that there was no statistical association between poor adherence to therapy and more severe clinical profiles. We observed an increase in the chance of death in patients with a cold/congested, hot/congested profile and in patients with low/moderate adherence to treatment. Conclusion: The study does not demonstrate a statistical correlation between the method (TMG) and the clinical profile of decompensation.