Isolamento de substâncias bioativos dos capítulos florais de Egletes viscosa L.

Abstract

Macela-da-Terra (Egletes viscosa) is a very common plant in the state of Ceara. Its floral chapters are used to prepare teas that help in the treatment of gastrointestinal disorders. Previous studies reports that the flowers of this plant are rich in ternatin, a bioactive flavonoid with gastroprotective activity. Considering the high pharmacological potential of ternatin, it is important to develop a method of extraction and purification of large amounts of ternatin that require few times and low cost. Thus, in the present study, was developed a methodology to isolation and purification of ternatin from a ethyl acetate fraction previously obtained of the flowers of macela-da-terra. After successive liquid-liquid partitions and recrystallization in MeOH was isolated the flavonoid ternatin in a high degree of purity, as determined by its 1H NMR spectrum. However, the method still needs to be improved in order to increase the yield of the process.