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dc.contributor.authorCosta, Renata Albuquerque-
dc.contributor.authorSousa, Oscarina Viana de-
dc.contributor.authorHofer, Ernesto-
dc.contributor.authorMafezoli, Jair-
dc.contributor.authorBarbosa, Francisco Geraldo-
dc.contributor.authorVieira, Regine Helena Silva dos Fernandes-
dc.date.accessioned2022-07-14T14:09:48Z-
dc.date.available2022-07-14T14:09:48Z-
dc.date.issued2017-
dc.identifier.citationCOSTA, Renata Albuquerque; SOUSA, Oscarina Viana de; HOFNER, Ernesto; MAFEZOLI, Jair; BARBOSA, Francisco Geraldo; VIEIRA, Regine Helena Silva dos Fernandes. Thiocarbamates from Moringa oleifera seeds bioactive against virulent and multidrug-resistant Vibrio specie. Biomed Research International, London, v. 2017, p. 1-6, 2017.pt_BR
dc.identifier.issn2314-6141-
dc.identifier.urihttp://www.repositorio.ufc.br/handle/riufc/67097-
dc.description.abstractProspect of antibacterial agents may provide an alternative therapy for diseases caused by multidrug-resistant bacteria. This study aimed to evaluate the in vitro bioactivity of Moringa oleifera seed extracts against 100 vibrios isolated from the marine shrimp Litopenaeus vannamei. Ethanol extracts at low (MOS-E) and hot (MOS-ES) temperature are shown to be bioactive against 92% and 90% of the strains, respectively. The most efficient Minimum Inhibitory Concentration (MIC) levels of MOS-E and MOS-ES against a high percentage of strains were 32 µg mL−1. Bioguided screening of bioactive compounds showed that the ethyl acetate fraction from both extracts was the only one that showed antibacterial activity. Vibriocidal substances, niazirine and niazimicine, were isolated from the aforementioned fraction through chromatographic fractionation.pt_BR
dc.language.isoenpt_BR
dc.publisherBiomed Research International,pt_BR
dc.subjectAntibioticpt_BR
dc.subjectAntibacterial agentspt_BR
dc.subjectSpeciation - Litopenaeus vannameipt_BR
dc.subjectAntibióticopt_BR
dc.subjectAntibacterianospt_BR
dc.subjectEspeciação - Litopenaeus vannameipt_BR
dc.titleThiocarbamates from Moringa oleifera seeds bioactive against virulent and multidrug-resistant Vibrio speciept_BR
dc.typeArtigo de Periódicopt_BR
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