Desenvolvimento e análise de estabilidade de xampu anticaspa com cetoconazol a 1%

Abstract

The use of products to give a cleansing and beauty aspect to the hair has been reported for a long time, but only around the 18th century were the first shampoo baths, and only in the 19th-century detergents were incorporated to produce the formula that was later dubbed 'shampoo'. In addition to removing dirt, these cosmetics sought to include other attractions such as a pleasant odour and specific effects on the hair. Currently, various types of shampoos are marketed, each with its particularities. With different price ranges, different physical states, multiple compositions, among others. Some of the formulas produced, in turn, have active ingredients that act in the dermal region of the hair, the scalp to treat infections. One example is a shampoo with ketoconazole, whose main purpose is to treat seborrheic dermatitis, having power beyond treating quickly and effectively relieving the effects caused by it. Ketoconazole has antifungal action; however, the problem must be initially analyzed to define whether this active is ideal for treating the type of infection that occurred. The Anti-Dandruff Shampoo with Ketoconazole 1% studied, in turn, had trials that attest to its quality, safety and efficacy. The tests carried out took into account physical-chemical, organoleptic and microbiological aspects. The variations found in the period, if not expected, did not compromise the quality of the product. During the studies, the occurred changes had their causes found, and some were mitigated. In addition, the adjustments that may occur to correct parameters such as viscosity or pH were taken into account. With the tests performed, it was concluded that the product can be produced and marketed and supports the appeal of "dermatologically tested".