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| Campo DC | Valor | Idioma |
|---|---|---|
| dc.contributor.author | Brito, Luana San de O. | - |
| dc.contributor.author | Pinto, Francisco das Chagas L. | - |
| dc.contributor.author | Moraes Filho, Manoel Odorico de | - |
| dc.contributor.author | Rocha, Danilo D. | - |
| dc.contributor.author | Mendoza, Maria Fernanda M. | - |
| dc.contributor.author | Ayala, Alejandro Pedro | - |
| dc.contributor.author | Bezerra, Beatriz Pinheiro | - |
| dc.contributor.author | Loiola, Maria Iracema B. | - |
| dc.contributor.author | Canuto, Kirley Marques | - |
| dc.contributor.author | Silveira, Edilberto R. | - |
| dc.contributor.author | Pessoa, Otilia Deusdenia L. | - |
| dc.date.accessioned | 2022-02-21T15:44:29Z | - |
| dc.date.available | 2022-02-21T15:44:29Z | - |
| dc.date.issued | 2020 | - |
| dc.identifier.citation | BRITO, Luana San de O. et al. Tropane alkaloids from the stem bark of Erythroxylum bezerrae. Phytochemistry, [s. l.], v. 178, p. 1-9, 2020. | pt_BR |
| dc.identifier.uri | http://www.repositorio.ufc.br/handle/riufc/64080 | - |
| dc.language.iso | en | pt_BR |
| dc.publisher | Phytochemistry | pt_BR |
| dc.rights | Acesso Aberto | pt_BR |
| dc.subject | Erythroxylum bezerrae Plowman | pt_BR |
| dc.subject | Erythroxylaceae | pt_BR |
| dc.subject | Tropane alkaloids | pt_BR |
| dc.subject | Cytotoxic activity | pt_BR |
| dc.title | Tropane alkaloids from the stem bark of Erythroxylum bezerrae | pt_BR |
| dc.type | Artigo de Periódico | pt_BR |
| dc.description.abstract-ptbr | Six previously undescribed tropane alkaloids, designated as erythrobezerrines A-F, were isolated from the EtOH extract from the stem bark of Erythroxylum bezerrae Plowman. Their structures were elucidated based on the interpretation of the NMR and MS data and in some instances, confirmed by X-ray diffraction analysis. The cytotoxicity of the isolated compounds was evaluated against the cancer cell lines L929, PC-3, HCT-116, SNB-19 and NCI-H460, but only erythrobezerrine C showed moderate activity with IC50 values of 3.38 and 5.43 μM for HCT-116 and NCI-H460, respectively | pt_BR |
| Aparece nas coleções: | DBIO - Artigos publicados em revista científica | |
Arquivos associados a este item:
| Arquivo | Descrição | Tamanho | Formato | |
|---|---|---|---|---|
| 2020_art_lsbrito.pdf | 6,03 MB | Adobe PDF | Visualizar/Abrir |
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