Please use this identifier to cite or link to this item:
http://repositorio.ufc.br/handle/riufc/5242| Type: | Artigo de Periódico |
| Title: | Susceptibility to caspofungin of Candida spp. strains isolated in Ceará, Northeastern Brazil |
| Authors: | Silva, C. Rocha da Silva Campos, R. de Sousa Santos Neta, M. Adalgiza dos Ângelo, M. Rozellê Ferreira Magalhães, H. Iury Ferreira Cavalcanti, B. Coêlho Moraes Filho, Manoel Odorico de Macedo, D. Silveira Nobre Júnior, Hélio Vitoriano |
| Keywords: | Candida;Aspergillus |
| Issue Date: | Dec-2011 |
| Publisher: | Journal de Mycologie Médicale |
| Citation: | SILVA,C. R. et al. Susceptibility to caspofungin of Candida spp. strains isolated in Ceará,Northeastern Brazil. Journal de Mycologie Médicale, v. 21, n. 4, p. 273-276, dez., 2011. |
| Abstract: | Caspofungin is an echinocandin prescribed for the treatment of invasive fungal infections caused by Candida spp. and Aspergillus spp. The aim of this study is to assess thedegree of susceptibility of Candida spp., isolated from blood cultures in the state of Ceará (Brazil) to caspofungin by the broth microdilution method. Thirty-three strains of Candida spp. were selected for the test (seven C. albicans, nine C. tropicalis and 17 C. parapsilosis); these strains are the most commonly isolates of fungal infections in Ceará. The results of susceptibility tests by broth microdilution can be read at 24 or 48 hours after testing, without compromising test interpretations. C. parapsilosis exhibited the highest MICs when compared with the MICs of caspofungin against C. albicans and C. tropicalis. |
| Abstract in French: | La caspofungine est une échinocandine prescrite pour le traitement des infections fongiques invasives causées par Candida sp. et Aspergillus sp. Le but de cette étude est d’évaluer le degré de sensibilité à la caspofungine de Candida sp., isolé à partir d’hémocultures dans l’état du Ceará (Brésil) par la méthode de microdilution. Trente-trois souches de Candida sp. ont été sélectionnées pour le test (sept C. albicans, neuf C. tropicalis et 17 C. parapsilosis) ; ces souches sont le plus souvent isolées dans des infections fongiques en Ceará. Les résultats des tests de sensibilité par microdilution peuvent être lus à 24 ou 48 heures après les tests, sans compromettre les interprétations du test. C. parapsilosis montre les CMI les plus élevées comparativement à celles de C. albicans et C. tropicalis pour la caspofungine. |
| URI: | http://www.repositorio.ufc.br/handle/riufc/5242 |
| ISSN: | 1156-5233 |
| Appears in Collections: | DMC - Artigos publicados em revistas científicas |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 2011_art_masantosneta.pdf | 247,84 kB | Adobe PDF | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.