Metástase linfonodal de adenoma pleomórfico recidivado : relato de caso

Abstract

Pleomorphic adenoma is the most common neoplasm of the major and minor salivary glands; however, its metastatic variant is rare. Thus, the purpose of this paper is to report a case of this entity. A 42-year-old female patient underwent a transoral resection of adenocarcinoma of minor salivary glands in left jugal mucosa in 2008. After 8 years, she presented tumor recurrence and metastasis to submandibular lymph nodes, which was identified as pleomorphic adenoma. The patient was submitted to resection of the lesion, with maxillectomy and modified radical emptying, with reconstruction from the masseter muscle flap. The patient was referred for adjuvant radiotherapy and has been free of disease for 1 year. The metastasis of pleomorphic adenomas manifests years after the primary tumor. The pathophysiological mechanism of dissemination is uncertain and tumor markers of greater aggressiveness for these adenomas are being studied. Therefore, the need for complete and technically perfect excision of the primary neoplasia is reaffirmed.