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http://repositorio.ufc.br/handle/riufc/5028
Tipo: | Artigo de Periódico |
Título : | Synergistic Effect of Antituberculosis Histoplasma capsulatum var. capsulatum Drugs and Azoles In Vitro against |
Autor : | Caetano, Érica Pacheco Cordeiro, Rossana de Aguiar Marques, Francisca Jakelyne de Farias Brilhante, Raimunda Sâmia Nogueira Silva, Kylvia Rocha de Castro e Mourão, Charles Ielpo Fechine, Maria Auxiliadora Bezerra Ribeiro, Joyce Fonteles Castelo-Branco, Débora de Souza Collares Maia Lima, Rita Amanda Chaves de Rocha, Jacó Ricarte Castro Rocha, Marcos Fábio Gadelha Sidrim, José Júlio Costa Mesquita, Jacó Ricarte Lima Monteiro, Andre Jalles |
Palabras clave : | Antibióticos Antituberculose;Azóis;Histoplasma |
Fecha de publicación : | jun-2011 |
Editorial : | Antimicrobial Agents and Chemotherapy |
Citación : | CAETANO, E. P. et al. Synergistic Effect of Antituberculosis Drugs and Azoles In Vitro against Histoplasma capsulatum var. capsulatum . Antimicrobial Agents and Chemotherapy, Washington, v. 55, n. 9, p. 4482-84, jun. 2011. |
Abstract: | This study evaluated in vitro interactions of antituberculosis drugs and triazoles against Histoplasma capsulatum. Nine drug combinations, each including an antituberculosis drug (isoniazid, pyrazinamide, or ethambutol) plus a triazole (itraconazole, fluconazole, or voriconazole), were tested against both growth forms of H. capsulatum. Stronger synergistic interactions were seen in isoniazid or pyrazinamide plus triazoles for the mold form and ethambutol plus voriconazole for the yeast-like form. Further studies should evaluate these combinations in vivo. |
URI : | http://www.repositorio.ufc.br/handle/riufc/5028 |
ISSN : | 0066-4804 |
Aparece en las colecciones: | DMC - Artigos publicados em revistas científicas |
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Fichero | Descripción | Tamaño | Formato | |
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2011_art_epcaetano.pdf | 142,11 kB | Adobe PDF | Visualizar/Abrir |
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