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http://repositorio.ufc.br/handle/riufc/30409| Type: | Artigo de Periódico |
| Title: | Effectiveness of metronidazole in the treatment of tumor wound odors |
| Other Titles: | Efetividade do metronidazol no tratamento de odores em feridas tumorais |
| Authors: | Barreto, Arthur Monte Marques, Antonio Dean Barbosa Cestari, Virna Ribeiro Feitosa Cavalcante, Rochelle da Costa Moreira, Thereza Maria Magalhães |
| Keywords: | Ferimentos e Lesões;Metronidazole;Odorantes;Wounds and Injuries |
| Issue Date: | 2018 |
| Publisher: | Rev Rene |
| Citation: | BARRETO, A. M. et al. Effectiveness of metronidazole in the treatment of tumor wound odors. Rev Rene, Fortaleza, v. 19, e3245, 2018. |
| Abstract in Brazilian Portuguese: | Objetivo: analisar as evidências da efetividade do Metronidazol no tratamento de odores em feridas tumorais. Métodos: revisão integrativa realizada nas bases de saúde e no portal PubMed. Os estudos foram avaliados pela Escala de Jadad (ensaios clínicos randomizados), Downs e Black (quase experimentais) e o Strengthening the Reporting of Observational studies in Epidemiology (observacionais). Amostra de dez estudos e considerouse como ponto de corte artigos que atingiram 50,0% dos critérios. Resultados: o Metronidazol se mostrou efetivo em 95,6% dos casos e a preparação em gel a 0,75% foi a mais utilizada nos estudos. Conclusão: as evidências apontam o metronidazol como seguro e eficaz no controle de odores em feridas tumorais, porém não há consenso sobre as formas de apresentação e vias de administração mais efetivas. A maioria dos estudos associa o surgimento de mau odor com o crescimento de bactérias anaeróbias no tecido tumoral. |
| Abstract: | Objective: to analyze the evidence of the effectiveness of Metronidazole in the treatment of odors in tumor wounds. Methods: this is an integrative review performed at the health databases and the PubMed portal. The studies were evaluated by the Jadad Scale (randomized clinical trials), Downs and Black (quasi-experiment) and the Strengthening the Reporting of Observational studies in Epidemiology (observational). A sample of the ten studies and articles were considered cut-off points that reached 50.0% of the criteria. Results: Metronidazole was effective in 95.6% of the cases and the gel preparation at 0.75% was the most used in the studies. Conclusion: the evidence indicates that metronidazole is safe and effective in the control of tumor wound odors, but there is no consensus on the most effective forms of presentation and administration routes. Most studies associate the appearance of bad odor with the growth of anaerobic bacteria in the tumor tissue. |
| URI: | http://www.repositorio.ufc.br/handle/riufc/30409 |
| ISSN: | 1517-3852 2175-6783 |
| Appears in Collections: | DENF - Artigos publicados em revistas científicas |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 2018_art_ambarreto.pdf | 231,03 kB | Adobe PDF | View/Open |
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