Abordagem diagnóstica clínico - laboratorial de sertolioma intratubular em cão criptoquídico

Abstract

Sertolioma is a common type of primary unilateral or bilateral testicular cancer, generally without signs that indicate the possibility of metastasis. This paper describes the clinical and laboratory diagnostic approach of a cryptorchid dog with sertolioma. The object of study was a male Pinscher dog, which reported the presence of a nodule in the inguinal region by its owner. Upon the nodule palpation during the physical examination, it was found the presence of edema and increased volume with firm consistency, but without fibrous features. Complete blood count, serum biochemical tests, ECG and echocardiogram, and fine - needle aspiration cytology were requested. Among other findings, cytology showed changes suggesting sertolioma: Numerous round and polygonal cells of large cytoplasm, displaying small vacuoles with reticular chromatin nucleiand evident nucleoli; fine bundles of fibrous tissue; and lymphocytes and neutrophils in hemorrhagic background rich in cell debris. The definitive diagnosis was made after orchiectomy through biopsy of the right testicular tumor, which showed neoplasia in malignant Sertoli cells, arranged in solid blocks fully occupying seminiferous tubules; necrotic foci; and bleeding, arousing intense subacute nflammatory process.