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http://repositorio.ufc.br/handle/riufc/18999| Type: | Artigo de Periódico |
| Title: | New terpenoids from Croton limae (Euphorbiaceae) |
| Authors: | Sousa, Antonio H. Silva Junior, José N. Guedes, Maria L. S. Braz-Filho, Raimundo Costa-Lotufo, Letícia V. Araújo, Ana J. Silveira, Edilberto R. Lima, Mary A. S. |
| Keywords: | Diterpenos;Diterpenes |
| Issue Date: | Aug-2015 |
| Publisher: | Journal of the Brazilian Chemical Society |
| Citation: | SOUSA, A. H. et al. New Terpenoids from Croton limae (Euphorbiaceae). Journal of the Brazilian Chemical Society, São Paulo, v. 26, n. 8, p. 1565-1572, aug., 2015. |
| Abstract: | An asymmetrical dimer of kaurane diterpene and monoterpene and four novel diterpenes were isolated from the roots of Croton limae, along with kaempferol-3-O-glucoside, ombuin- 3-O-rutinoside and acetyl aleuritolic acid. The cytotoxic activity of the kaurane diterpene was evaluated against colorectal adenocarcinoma (HCT-116), ovarian carcinoma (OVCAR-8) and glioma (SF-295) cell lines, exhibiting IC50 values of 7.14, 8.19 and > 10 µg mL−1, respectively. |
| URI: | http://www.repositorio.ufc.br/handle/riufc/18999 |
| ISSN: | Print version 0103-5053 On-line version 1678-4790 |
| Appears in Collections: | PPGF - Artigos publicados em revistas científica |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 2015_art_ahsousa.pdf | 229,2 kB | Adobe PDF | View/Open |
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