Soroprevalência de vírus Zika em mulheres em idade fértil na Unidade Básica de Saúde Graciliano Muniz, Fortaleza, Ceará

Abstract

The Zika virus (ZIKV) is a RNA virus of the Flavivirus family, Flavivirus, transmitted mainly by mosquitoes of the genus Aedes, which was discovered in 1947 in the Zika Forest, Uganda, in 1964 in the same country where it was characterized as mild self-limited, characterized by the appearance of maculopapular spots. The first major outbreak of the virus The zika occurred in 2007 on Yap island, Micronesia, but it was in 2013, during the outbreak of French Polynesia, that had several neurological complications when being associated with Zika, such as Guillain-Barré syndrome. In 2015, disproportionate cases of microcephaly in gestures and newborns began to be reported in Northeast Brazil. By the end of 2016 there were 1,624 confirmed cases of microcephaly, which had their cause related to the Zika virus. In the state of Ceará, in the year 2018, 558 cases were reported, of which 6.6% were confirmed. The present study aimed to estimate a general serology of the Zika virus (ZIKV) in women aged 15 to 39 from the Graciliano Muniz health series in the city of Fortaleza, Ceará. In the year 2018, samples of peripheral venous blood were collected from women attending the Graciliano Muniz Basic Health Unit, located in the neighborhood of Conjunto Esperança, in the city of Fortaleza (Ceará), and then referred to the Mycobacteria Laboratory. of the Federal University of Ceará (LabMico / UFC) for aliquoting and storage. Between 10/01/2018 to 10/24/2018, the ELISA test for IgG-Anti-Zika and IgM-Anti-Zika was carried out at the Central Laboratory of the State of Ceará (LACEN/CE). Of the total, 24.20% (68/281) of the patients analyzed were IgG positive for Zika virus and 1.07% (3/281) were IgM positive. Tax on the fact of having a very small evaluation area has the capacity of 8.11% of cases notified throughout the state, which is an underreporting of Zika fever cases in the state of Ceará. The present study demonstrated that 24.56% of the children were affected by the virus at some point in their life.