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http://repositorio.ufc.br/handle/riufc/9938| Type: | Artigo de Periódico |
| Title: | A convenient synthesis and cytotoxic activity of 3-aryl-5-pentyl-1,2,4-oxadiazoles from carboxylic acid esters and arylamidoximes under solvent-free conditions |
| Authors: | Barros, Carlos Jonnatan Pimentel Souza, Zilyane Cardoso de Freitas, Jucleiton José Rufino de Silva, Paulo Bruno Norberto da Militão, Gardenia Carmen Gadelha Silva, Teresinha Gonçalves da Freitas, Juliano Carlo Rufino Freitas Filho, João Rufino de |
| Keywords: | Ésteres;Frutas |
| Issue Date: | Mar-2014 |
| Publisher: | Journal of the Chilean Chemical Society |
| Citation: | BARROS, C. J. P. et al. A convenient synthesis and cytotoxic activity of 3-aryl-5-pentyl-1,2,4-oxadiazoles from carboxylic acid esters and arylamidoximes under solvent-free onditions. Journal of the Chilean Chemical Society, Concepcíon, v. 59, n. 1, p. 2359-2362, mar. 2014. |
| Abstract: | The synthesis of 3-aryl-5-pentyl-1,2,4-oxadiazoles from carboxylic acid esters and arylamidoximes in the presence of potassium carbonate is described. The reaction was carried out in a microwave oven without any solvent in much shorter time and in good yields. The structures of the synthesized compounds were elucidated using IR, 1H and 13C NMR spectroscopy and elemental analysis and their antiproliferative activities was evaluated against three different human cell lines. |
| URI: | http://www.repositorio.ufc.br/handle/riufc/9938 |
| ISSN: | 0717-9707 |
| Appears in Collections: | DFIFA - Artigos publicados em revista científica |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 2014_art_gcgmilitao.pdf | 394,85 kB | Adobe PDF | View/Open |
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