Utilização na medicina popular, potencial terapêutico e toxicidade em nível celular das plantas Rosmarinus officinalis L., Salvia officinalis L. e Mentha piperita L. (Família Lamiaceae)

Abstract

This study aimed to perform an extensive, but objective, literature review on the use in folk medicine, therapeutic potential and toxicity at the cellular level, of Rosmarinus officinales, Salvia officinales and Mentha piperita belonging to the family Lamiaceae. These plants are widely cultivated and used in folk medicine, and studied by researchers worldwide for its therapeutic and toxicological potential. For this research, the bases of SciELO, PubMed and Google Scholar were consulted. After analyzing the articles it was found that these plants, mainly by the action of its essential oils, terpenes and flavonoids phytochemical in their constitutions are efficient in the treatment of diseases of the digestive apparatus, circulatory and respiratory, and nervous system. As for toxicity at cellular level, the three plants have antiproliferative, cytotoxic, genotoxic and mutagenic effects to strains of normal and tumor cells. From this review, it is reinforced the importance of these plants in healing and alleviation diseases and the potential for being used in the future as a chemopreventive.