Influência do coping religioso-espiritual na qualidade de vida e adesão terapêutica de pacientes com doença inflamatória intestinal

Abstract

Inflammatory Bowel Disease (IBD) is associated with elevated levels of anxiety and depression, and a reduction in health-related quality of life (HRQoL). Non-adherence to treatment is also frequent in IBD and compromises outcomes. Religious coping plays a role in the adaptation to several chronic diseases. However, the influence of religious coping on IBD-related psychological distress, HRQoL and treatment adherence remains unknown. The aim of this study is to assess the influence of religious coping on psychological distress, adhesion to treatment and quality of life of IBD patients. Method: This cross-sectional study recruited 147 consecutive patients with either Crohn`s Disease or Ulcerative Colitis. Sociodemographic data, disease-related variables, psychological distress (Hospital anxiety and depression scale), religious coping (Brief RCOPE Scale), HRQOL (WHOQOL-Bref) and adherence (8-item Morisky Medication Adherence Scale) were assessed. Hierarchical multiple regression models were used to evaluate the effects of religious coping on IBD-related psychological distress, treatment adherence and HRQoL. Results: Positive RCOPE was independently associated with anxiety (b=-0.256; p=0.007) as well as with overall, physical and mental health HRQOL. Religious struggle was significantly associated with depression (b=0.307; P<.001) and self-reported adherence (b=-0.258; P=0.009). Finally, anxiety symptoms fully mediated the effect of positive religious coping on overall HRQoL. Conclusion: Religious Coping is significantly associated with psychological distress, HRQOL and adherence in IBD. The assessment and management of religious coping has the potential to improve IBD-related outcomes.