Mobilidade e a qualidade de vida em pacientes onco hematológicos no pré-transplante de medula óssea do Centro de Hematologia e Hemoterapia do Ceará.

Abstract

Introduction: Bone marrow transplantation is a treatment option in hematological neoplasms and can be allogenic or autogenous. The serious effects of treatment are associated with basic diseases, which can cause: fatigue; loss of muscle mass; reduction of functional capacity; weakness and decreased quality of life in the long term. Objective: To verify the relationship between functional mobility and quality of life (QOL) in hematological patients in pre-bone marrow transplantation. Methods: This is a cross-sectional validation study conducted at a reference Hematology and Hemotherapy Center of Ceará in Fortaleza/Ceará from June 2019 to October 2022. An evaluation form with demographic data was applied, after the WHO Disability Assessment Schedule 36 items (WHODAS 2.0), the Timed-Up-and-Go test (TUG) and the Medical Outcome Study Short Form 36 (SF-36). Results: Sixty-one individuals were evaluated, most of them women (n=33), with leukemia (n=16), with a mean age of 42.4 14.6 years. The participants answered the questions of the main instrument in two distinct moments in time. In WHODAS 2.0 the aspects interpersonal relations and self-care were the ones that presented the least dysfunction and the aspects of work activities and life activities presented the greatest dysfunctions. The results expressed a strong ICC value (ICC=0.789), which shows a good test-retest reproducibility in the research. The instrument proved to be highly consistent being expressed by a Cronbach’s alpha greater than 0.7 in almost all WHODAS 2.0 domains. Conclusion: WHODAS 2.0 proved to be a valid, reliable and sensitive instrument to analyze the functionality of patients in bone marrow pre-transplantation.