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http://repositorio.ufc.br/handle/riufc/5280| Type: | Artigo de Periódico |
| Title: | In vitro effect of Sulfamethoxazole-Trimethoprim against Histoplasma capsulatum var. capsulatum |
| Authors: | Brilhante, Raimunda Sâmia Nogueira Fechine, Maria Auxiliadora Bezerra Cordeiro, Rossana de Aguiar Rocha, Marcos Fa ́bio Gadelha Ribeiro, Joyce Fonteles Monteiro, André Jalles Lima, Rita Amanda Chaves de Mesquita, Jaco ́ Ricarte Lima Camargo, Zoilo Pires de Sidrim, Jóse Júlio Costa |
| Keywords: | Histoplasma;HIV |
| Issue Date: | Sep-2010 |
| Publisher: | Antimicrobial Agents and Chemotherapy |
| Citation: | BRILHANTE, R. S. N. et al. In vitro effect of Sulfamethoxazole-Trimethoprim against Histoplasma capsulatum var. capsulatum. Antimicrobial Agents and Chemotherapy, v. 54, n. 9, p. 3978-3979, set. 2010. |
| Abstract: | This study evaluated the in vitro effect of sulfamethoxazole-trimethoprim against Histoplasma capsulatum var. capsulatum isolated from HIV-positive patients. The drugs were tested by microdilution testing in accordance with the CLSI guidelines. All of the strains were inhibited by sulfamethoxazole-trimethoprim, with MIC ranges of 0.039 (sulfamethoxazole)/0.0078 (trimethoprim) mg/ml to 0.625/0.125 mg/ml for mycelial forms and 0.0025/ 0.0005 to 0.02/0.004 mg/ml for yeast-like forms. However, in vivo studies are necessary to evaluate the significance of these results. |
| URI: | http://www.repositorio.ufc.br/handle/riufc/5280 |
| ISSN: | 0066-4804 |
| Appears in Collections: | DMC - Artigos publicados em revistas científicas |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 2010_art_raclima.pdf | 44,59 kB | Adobe PDF | View/Open |
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