http://repositorio.ufc.br/handle/riufc/41717 2026-07-19T01:27:40Z http://repositorio.ufc.br/handle/riufc/86845 Título: Prevalence of permanent teeth avulsion in a brazilian trauma center: a 12 year retrospective study Autor(es): Barbosa, Adriana Kelly de Sousa Santiago; Rebouças, Pedro Diniz; Rodrigues, Lorena Walesca Macedo; Gondim, Juliana Oliveira; Moreira Neto, José Jeová Siebra Abstract: Objectives: The aim of this study is to perform a retrospective study of cases of avulsion of permanent teeth in patients from 12 years of the Oraldental Trauma Center (CENTRAU) of the School of Dentistry of Faculty of Pharmacy, Dentistry and Nursing in Federal University of Ceara. Material and Methods: A retrospective transversal study characterized by direct observation of dental records was performed of a spontaneous demand sample of dental trauma victims who presented to the Oraldental Trauma Center of UFC (CENTRAU) during the period from May 2001 to May 2013. Results: The analysis was done on 1,104 records, in which 66 patients reported having been victims of avulsion with 88 avulsed permanent teeth with ages ranging between 6 and 30 years. Among the 88 avulsed teeth, 59 (67.04%) were replanted. Only in 9 (15.5%) cases replantation was immediate. The storage medium that was the most widely used was the oral cavity by 8 (30.7%) patients. In 26 (39.4 %) cases, the cause of avulsion was falling to the ground. Conclusion: In this study, it was clear that cases of avulsion in CENTRAU corresponded to a low occurrence of all cases seen in the center. Tipo: Artigo de Periódico 2015-01-01T00:00:00Z http://repositorio.ufc.br/handle/riufc/82680 Título: Antinociceptive Effect of the Monoterpene R-()-Limonene in Mice Autor(es): Amaral, Jeferson Falcão do; Silva, Maria Izabel Gomes; Neto, Manuel Rufino de Aquino; Neto, Paulo Florentino Teixeira; Moura, Brinell Arcanjo; Melo, Carla Thiciane Vasconcelos de; Araújo, Fernando Luiz Oliveira de; Sousa, Damião Pergentino de; Vasconcelos, Patrícia Freire de; Vasconcelos, Silvânia Maria Mendes de; Sousa, Francisca Cléa Florenço de Abstract: In the present study were studied the antinociceptives properties of monoterpene R-()-limonene (LM) in chemical and thermal models of nociception in mice. The R-()-limonene was administered, intraperitoneally(i.p.), at doses of 25 and 50 mg/kg. The results showed significant inhibition produced on chemical nociception induced by intraperitoneal acetic-acid and in the second phase of subplantar formalin test, but did not manifest a significant effect in hot-plate test. The R-()-limonene-induced antinociception in second phase of formalin test was insensitive to naloxone (1 mg/kg, s.c.). It was also demonstrated that R-()-limonene (25, 50 mg/kg) neither significantly enhanced the pentobarbital-sleeping time nor impaired the motor performance in rota-rod test, indicating that the observed antinociception is unlikely to be due to sedation or motor abnormality. In conclusion it may be suggested that the R-()-limonene presented antinociceptive activity and that, probably, this action can be related with peripheral analgesia, but, not with the stimulation of opioids receptors. Tipo: Artigo de Periódico 2007-01-01T00:00:00Z http://repositorio.ufc.br/handle/riufc/82678 Título: Polimorfismo do gene do receptor de progesterona (PROGINS) em mulheres com câncer de mama. Estudo caso-controle Autor(es): Linhares, José Juvenal; Silva, Ismael Dale Cotrim Guerreiro da; Souza, Naiara Correa Nogueira de; Noronha, Emmanuelle Coelho; Ferraro, Odair; Baracat, Fausto Farah Abstract: to analyze the correlation between PROGINS polymorphism and breast cancer. Methods: a case-control study was carried out from April to October 2004. The genotypes of 50 women with breast cancer and 49 healthy women were analyzed. The 306-base pair Alu insertion polymorphism in the G intron of progesterone receptor gene was detected by polymerase chain reaction and analyzed on 2% agarose gel stained with ethidium bromide. The control and experimental groups were compared regarding genotypes using the statistical Epi-Info 6.0 program and for frequencies the exact Fisher test or χ2 test were used. p value smaller p than 5% was considered to be significant. Results: in relation to PROGINS we found in the studied population a prevalence of 62 (62.6%) wild homozygous, 35 (35.3%) heterozygous individuals and two (2.1%) cases with the presence of the mutation. Regarding PROGINS polymorphism, significance was not evidenced when cases and controls were compared, as related to homozygosis (62 vs 65.3%), heterozygosis (36 vs 34,6%) or the mutation (2.0 vs 2.1%), with p=0.920 (OR=1.01), 0.891 (OR=1.06), and 0.988 (OR=1.10), respectively. Conclusions: the results show that single-gene PROGINS polymorphism does not confer a substantial risk of breast cancer to its carriers. Tipo: Artigo de Periódico 2005-01-01T00:00:00Z http://repositorio.ufc.br/handle/riufc/80679 Título: Genetic polymorphism of GSTM1 in women with breast cancer and interact with reproductive history and several clinical pathologies Autor(es): Linhares, José Juvenal; Silva, Ismael Dale Cotrim Guerreiro da; Souza, Naiara C. Nogueira de; Noronha, Emmanuelle Coelho; Ferraro, Odair; Carvalho, Cristina Valleta de; Baracat, Edmund Chada; Baracat, Fausto Farah Abstract: Due to the conflicting results regarding the association between breast cancer and the GSTM1 null mutation, our aim was to research this association in a Brazilian population and correlations with smoking, reproductive history and several clinical pathologies. A case-control study was performed on 105 women with breast cancer and 278 controls. Extraction of DNA was accomplished according to the protocol of the GFX® kit and polymorphism analysis by the PCR technique. The control and experimental groups were compared and statistical analysis assessed by X2 or Fisher’s exact test. The deletion in the GSTM1 gene in the breast cancer group had a prevalence of 32 (30.4%) individuals with the presence of null mutation. In the control group, the null mutation was present in 104 (37.4%) women. Upon comparison of the two groups, no statistically significant difference of the GSTM1 gene was observed, with an odds ratio (OR) of 0.74, 95%, confidence interval (CI) 0.45 - 1.20, p = 0.277. The results conclusively show that single gene GSTM1 polymorphisms do not confer a substantial risk of breast cancer to its carriers. Furthermore, in this study no correlation was found between GSTs and smoking, reproductive history and several clinical pathologies with respect to cancer risk. Tipo: Artigo de Periódico 2005-01-01T00:00:00Z