http://repositorio.ufc.br/handle/riufc/391 2026-04-08T22:39:19Z http://repositorio.ufc.br/handle/riufc/65513 Título: Aneurisma de artéria pulmonar como apresentação clínica de uma doença de Behçet: a propósito de um caso Autor(es): Rodrigues, Lara Martins; Liberato, Benedita Tatiane Gomes; Carneiro, Ana Rita Sampaio; Paixão, Miguel Wesley Nogueira; Ponte, Maycon Fellipe da Abstract: Objective: To present clinical aspects and radiological changes observed in a case of Behçet’s disease. Methodology: The research was conducted through the investigation of a patient diagnosed with Behçet’s disease presenting with pulmonary artery aneurysm. Case description: Patient with a history of recurrent painful oral and genital ulcers. He presented with edema and pain in the cervical region, being diagnosed with internal jugular vein thrombosis and right brachiocephalic vein. The patient developed dyspnea, chest pain, hemoptysis, hematemesis, and pulmonary artery aneurysm was diagnosed, as well as painful ulcers, and Behçet’s disease was diagnosed. Discussion: From the International Study Group for Behçet’s Disease classification, the presence of recurrent oral ulcers and two of the following alterations - genital ulcers, typical eye lesions (uveitis, retinal vasculitis), characteristic skin lesions, or a positive patergia test define the diagnosis of Behçet’s disease. Although rare, affecting less than 5% of patients, pulmonary artery involvement is the most feared form of vascular complication. Conclusion: We can conclude that it is important to consider the diagnosis of Behçet, as this pathology can affect several vessels of any caliber in the body and may result in thrombophlebitis, arterial stenosis, occlusions and aneurysms. Tipo: Artigo de Periódico 2022-04-01T00:00:00Z http://repositorio.ufc.br/handle/riufc/65489 Título: Protocolo de cuidado ocular em pacientes internados nas unidades de tratamento intensivo Autor(es): Aragao, Ricardo Evangelista Marrocos de; Araruna, Loianne Pereira; Sousa, Mayara Pereira; Santos, Erika Andrade; Gomes, Lorena Maria Araújo Abstract: Patients in intensive care unit require a high standard of medical and nursing practice, they are critically ill and dependent on technology and medication, however, they are potentially vulnerable to ocular surface disease, mostly those sedated and at mechanical ventilation,which are at risk for exposure keratopathy. This condition predisposes to microbial keratitis that may lead to corneal perforation and permanent visual loss. For these reasons eye care with regular cleaning of the eyes, installation of lubricating drops and ointments are recommended. Meta-analysis showed that moisture chambers are significantly better than lubrification at prevent exposure keratopathy. We reviewed some studies that showed the superiority of the moisture chamber in prevent ocular surface disease in patient in intensive care units. Tipo: Artigo de Periódico 2022-04-01T00:00:00Z http://repositorio.ufc.br/handle/riufc/64760 Título: Resultados do transplante alogênico de células tronco hematopoiéticas em síndrome mielodisplásica do Hospital Universitário Walter Cantídio Autor(es): Cordeiro, Missielle Duarte; Gonçalves, Romélia Pinheiro; Duarte, Fernando Barroso Abstract: Introduction: Myelodysplastic syndromes (MDS) are a heterogeneous group of clonal hematopoietic disorders that are more likely to progress to acute myeloid leukemia (AML). Alogenic Haematopoietic Stem Cell Transplantation (HSCT) represents the most effective curative treatment for MDS to date. Objectives: To describe the profile of patients with MDS, who performed HSCT at the Walter Cantídio Universitary Hospital (HUWC) in Fortaleza, Ceará. Methodology: Retrospective observational and descriptive study with eleven patients with newly diagnosed MDS who performed HSCT in the period of February, 2015 to June, 2018. Results: Total of eleven patients, age at diagnosis from nineteen to sixty-six years (mean age 46 years). Three deletion patients of the 5q (two with additional alterations), four hypocellular, one with multiple lineage dysplasia (p53 positive in immunohistochemistry), two with excess type 2 blasts, one with ring sideroblasts (low risk). Ten related donors with peripheral blood cell source and one non-related source of bone marrow. Deaths: a patient with excess blasts and a patient with multilinear dysplasia. Conclusion: It is possible to identify patients with low-risk MDS who have an indication for Alogenic Hematopoietic Stem Cell Transplantation. Additional cytogenetic abnormalities at the 5q deletion had no negative impact. We also reinforced the prognostic significance of p53. Tipo: Artigo de Periódico 2022-03-01T00:00:00Z http://repositorio.ufc.br/handle/riufc/64335 Título: Síndrome mielodisplásica variante hipoplásica: análise estatística no serviço de transplante de medula óssea do Hospital Universitário Walter Cantídio Autor(es): Martins, Henrique Girão; Barroso, Karine Sampaio Nunes; Leitão, João Paulo de Vasconcelos; Araujo, Beatriz Stela Gomes de Souza Pitombeira; Duarte, Fernando Barroso Abstract: Objectives: To analyze, in patients with myelodysplastic syndrome (MDS) hypoplastic variant of the Bone Marrow Transplant service, the response to the transplant and perform a comparison with data from the MDS Latin American database. Methodology: Analytical, cross-sectional and retrospective study by analyzing medical records, including all patients diagnosed with MDS undergoing bone marrow transplantation, evaluation of post-transplantation follow-up, overall survival and complications. Comparison with data from the database of the MDS Latin American Society. Statistical analysis using the JAMOVI and MedCalc programs. Results: A total of 13 MDS patients received an allogenic bone marrow transplant, of which 6 had hypoplastic variant, corresponding to 46.15%. Compared to data from the Latin American database, this percentage is only 12.75%. Conclusions: Our service presented a higher frequency of hypoplastic variant MDS than that described in the medical literature, which corresponds to only 10-15%. Of the 6 patients with hypoplastic MDS, two died, reaching 33.3% against 13.5% in the Latin American database. The other transplanted patients are in remission so far with an overall 2-year survival rate of 83.3%, showing good results compared to the world literature. Tipo: Artigo de Periódico 2022-03-01T00:00:00Z