Avaliação da solubilidade de cimentos obturadores dos canais radiculares à base de silicato de cálcio

2025-07-17T18:46:41Z

Título: Avaliação da solubilidade de cimentos obturadores dos canais radiculares à base de silicato de cálcio Autor(es): Borges, Roberto Pinheiro Abstract: In this study, it was evaluated the solubility of MTA Fillapex and iRoot SP sealers compared with AH Plus and MTA Sealapex, following n° 57 ANSI/ADA Specification. It were also carried out a chemical analysis by atomic absorption spectrometry and EDS-X, and morphological structure of the sealers were assessed by SEM. Ten samples of each sealer, 1.5 mm thick and 7.75 mm diameter, were made from Teflon molds. The specimens were weighed and immersed in 7.5 mL of distilled water for seven days. After this, they were removed from molds, dried and weighed. The solubility was obtained based on the mass loss, expressed as a percentage of original mass. Immersion liquids were subjected to spectrometry to detect the presence of Ca2+, K+, Zn2+, Ni2+, Na+ and Pb2+ ions. The sealers samples before and after the solubility test were analyzed in the external and internal surface by EDS-X and SEM. Data were analyzed by ANOVA and Tukey test (p<0.05). Regarding the solubility (%), iRoot (20.64 ± 1.42) and MTA Fillapex (14.89 ± 0.73) had the highest mean values and were statistically different among themselves and from the other cements (p<0.05). The Sealapex achieved intermediate values (5.65 ± 0.80) (p<0.05). AH Plus and MTA were statistically different from the others, and in accordance with ANSI/ADA standards. iRoot SP, Fillapex MTA, MTA and Sealapex had higher release of Ca2+ ion, unlike AH Plus. SEM showed morphological changes after the solubility test and EDS-X identified the presence of Ca2+ on the surfaces of the tested sealers, being the lowest level in AH Plus. High levels of carbon were observed in all sealers, except for the MTA. It was concluded that the calcium silicate based sealers did not fulfill the requirements of n° 57 ANSI/ADA Specification in relation to solubility. Tipo: Tese

Avaliação de parâmetros salivares, sorológicos e alimentares em indivíduos com e sem diabetes Mellitus tipo 1

2021-09-08T12:01:44Z

Título: Avaliação de parâmetros salivares, sorológicos e alimentares em indivíduos com e sem diabetes Mellitus tipo 1 Autor(es): Martins, Renata Asfor Rocha Carvalho Abstract: The present thesis has objectives divided into two chapters. Chapter 1 aims, through a systematic review with meta-analysis, to investigate whether diabetes mellitus type 1 (DM1) promotes changes in salivary levels of immunoglobulins (Ig) A, G and M when compared to that in individuals without DM1. The search strategy was performed in eight databases and gray literature, with nine studies being selected. Diabetic patients had a significant reduction in salivary flow (p=0.0008; Cohen's d = -0.19, 95% CI= -0.33, -0.05), but not significant enough to modify the IgA concentration (p=0.120; Cohen's d) = 0.58, 95% CI = -0.15, 1.32). However, DM1 increased IgA concentration by reducing salivary flow (Cohen's d = 0.84; 95% CI = 0.36, 1.32), with a strong estimate of effect (p=0.0006). Regarding IgG, no significant change was observed with DM1 in the patients' saliva (p=0.420). There was no significant variation in salivary IgM levels (p=0.300). Chapter 2 aimed to evaluate the association between salivary parameters: glucose (GS), flow, pH and proteins concentration; fasting and postprandial blood glucose; glycated hemoglobin; caries (CI), plaque (PI) and gingival bleeding (BI) indexes; and diet in children with (CDM1) and without (SDM1) DM1. The CDM1 and SDM1 groups were composed of 36 and 49 patients, respectively, matched for sex and age. For the evaluation of CI, PI and BI, a clinical examination was performed. The dietary pattern was obtained through the diet diary for the 24 hours prior to the appointment. Unstimulated total saliva was collected. Salivary protein concentration was analyzed by the bicinchoninic acid method. The Kolmogorov-Smirnov, Mann-Whitney and Spearman tests were used, considering p<0.05 and Statistical Packcage for the Social Sciences (SPSS®) software. SG, CI, PI and BI were submitted to the multiple linear regression model. There was no difference in mean salivary flow (p=0.649), CI (p=0.868), IP (p=0.618) and protein concentration (p=0.712). CDM1 had lower BI (p=0.031) and pH (p<0.001), higher values for mean number of meals (p<0.001) and carbohydrate-based meals (p<0.001), lower mean of intervals (p<0.001) and higher SG (p=0.036). Salivary glucose was directly correlated with fasting glucose (p=0.043) in CDM1 and showed positive collinearity with fiber count (p=0.018) and fasting glucose (p=0.048). In the CDM1 group, female gender (p=0.033) was significantly associated with plaque index, while the number of meals with sucrose showed inverse collinearity with this parameter (p=0.046) and pH (p=0.034) showed direct collinearity. The bleeding index showed direct collinearity with age (p=0.043) and with postprandial blood glucose (p=0.023). It was concluded, then, that salivary glucose was not associated with the other variables in SDM1, but with fasting glucose and diet in CDM1. Future studies are needed to confirm the use of salivary glucose in the early diagnosis and monitoring of DM1. The findings of the present research suggest that more studies with similar saliva sampling methods would be carried out. Tipo: Tese

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Avaliação da solubilidade de cimentos obturadores dos canais radiculares à base de silicato de cálcio

Avaliação de parâmetros salivares, sorológicos e alimentares em indivíduos com e sem diabetes Mellitus tipo 1