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Título em portugués: In vitro activities of amoxicillin-clavulanate, doxycycline, ceftazidime, imipenem, and trimethoprim-sulfamethoxazole against biofilm of Brazilian strains of Burkholderia pseudomallei
Autor: Bandeira, Tereza de Jesus Pinheiro Gomes
Moreira, Camila Alencar
Brilhante, Raimunda Sâmia Nogueira
Castelo-Branco, Débora de Souza Collares Maia
Araújo Neto, Manoel Paiva de
Cordeiro, Rossana de Aguiar
Rodrigues, Terezinha de Jesus Santos
Rocha, Marcos Fábio Gadelha
Sidrim, José Júlio Costa
Palabras clave : Amoxicilina
Doxiciclina
Fecha de publicación : nov-2013
Editorial : Antimicrobial agents and chemotherapy
Citación : BANDEIRA, T. J. P. G. et al. In vitro activities of amoxicillin-clavulanate, doxycycline, ceftazidime, imipenem, and trimethoprim-sulfamethoxazole against biofilm of brazilian strains of burkholderia pseudomallei. Antimicrobial Agents and Chemotherapy, Bethesda, v. 57, n. 11, p. 5771-3, nov. 2013.
Resumen en inglés: This study aimed at investigating the in vitro activities of amoxicillin-clavulanate, doxycycline, ceftazidime, imipenem, and trimethoprim- sulfamethoxazole against Burkholderia pseudomallei in planktonic and biofilm forms, through broth microdilution and resazurin-based viability staining, respectively. In planktonic growth, the strains were susceptible to the drugs, while in biofilm growth, significantly higher antimicrobial concentrations were required, especially for ceftazidime and imipenem, surpassing the resistance breakpoints. These results highlight the importance of the routine evaluation of biofilm antimicrobial susceptibility.
URI : http://www.repositorio.ufc.br/handle/riufc/8552
metadata.dc.type: Artigo de Periódico
ISSN : 0066-4804 Impresso
Aparece en las colecciones: DMC - Artigos publicados em revistas científicas

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