Avaliação da atividade fotoprotetora e antioxidante in vitro dos extratos aquosos de Schinopsis brasiliensis (Baraúna): desenvolvimento de uma emulsão fotoprotetora

Abstract

The caatinga is an ecological region that is located in the semi-arid region of the Brazilian Northeast, with its diversity of species, is Schinopsis brasiliensis, better known as baraúna, characteristic of being a tall tree, being able to reach 15 meters in height with 60 centimeters of diameters, in its chemical composition can find flavonoids, phenols, tannins and tripertens, being gallic acid the major component of the plant, aromatic substances that have a capacity of absorption of UV light and antioxidant power. Brazil is a country that addresses issues related to health, health, safety, health and wellness, bringing health benefits, as they are responsible for triggering the early emergence, depletion of the immune system, skin cancer, among others. Thus, the objective of this study was to evaluate the in vitro antioxidant and photoprotective potential of the aqueous extracts of the stem bark and the leaf of Schinopsis brasiliensis and its incorporation into a photoprotective emulsion. The antioxidant activity was determined by test, DPPH and lipid peroxidation, and the first test demonstrated an IC50 of 0.8 μg/ml and 4.38 μg/ml for leaf and stem bark, respectively, demonstrating the excellent antioxidant power of both extracts, the second test has an inhibition result of 81% and 78.6% for leaf and stem bark, respectively, reaffirming the excellent antioxidant power of the extracts. The in vitro SPF of extracts and formulations were developed by the spectrophotometric method developed by Mansur et al. (1986). The assay was conducted as one of the best extracts 6.3 and 4.7 for the leaf and the stem bark, and a photoprotective emulsion was prepared using extract coffee-table yarn in four 10%, 5%, 2.5% and 0.2%, the SPF was 2.01; 0.97; 0.24 and 0, respectively. Although the FPS values of the formulations are not significant significant, they should be reduced or extremely antioxidant from both extracts, noting that the 2.01 FPS formulation allows the extract to be indicated in multifunctional cosmetic formulations