Desenvolvimento e estudo de estabilidade preliminar de um gel creme fotoprotetor oil free FPS 30 a ser comercializado na Farmácia Escola da UFC

Abstract

RDC nº 629/2022 defines sunscreen as "any cosmetic preparation intended to come into contact with the skin and lips, with the exclusive or main purpose of protecting it against UVB and UVA radiation, absorbing, dispersing or reflecting radiation". In the pandemic scenario caused by SARS-CoV-2, there was a shortage of some raw materials by suppliers. As a result, Pharmacy School (UFC) was temporarily unable to produce and sell this product. In view of this, the development of a new formulation is justified by the need for Pharmacy School (UFC) to have sunscreen in its portfolio, to meet the demand of consumer public. Thus, the objective of this work was to develop a photoprotector to be sold at Farmácia Escola. The choice of formulation components was based on market research that evaluated the composition and filters used in ten different photoprotectors from multinational brands and the excipients already available at Pharmacy School (UFC). Two different formulations were produced, F1 and F2 (with Silicone DC 245) and the physical-chemical characterization of each was carried out at time zero. The photoprotector developed was presented as a pale yellow cream gel with a mild vanilla odor, with a dry touch and a reduction in brightness after application, with SPF 30. When carrying out the preliminary stability study, it did not suffer alterations in its organoleptic and in the pattern of size and distribution of micelles. Based on the Sensory Panel, in which the sensory perception of Pharmacy students was evaluated, the F2 formulation was chosen to continue the stability studies and be produced and marketed at the Pharmacy School of the UFC, because it presented a more satisfactory performance.