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Title in Portuguese: Histoplasmin survey in HIV-positive patients : results from an endemic area in northeastern Brazil
Author: Bezerra, Fabrícia Salvador
Zancopé-Oliveira, Rosely Maria
Brilhante, Raimunda Sâmia Nogueira
Wanke, Bodo
Mota, Rosa Maria Salani
Ramos, Ana Paula Gomes
Ramos Júnior, Alberto Novaes
Façanha, Mônica Cardoso
Leitão, Terezinha do Menino Jesus Silva
Keywords: HIV
Síndrome da Imunodeficiência Adquirida
Issue Date: Jul-2013
Citation: BEZERRA, F. S. et al. Histoplasmin survey in HIV-positive patients : results from an endemic area in northeastern Brazil. Rev. Inst. Med. Trop. Sao Paulo, SP, v. 55, n. 4, p. 261-265, jul./ago., 2013.
Abstract: Background. Disseminated histoplasmosis is common in AIDS patients with advanced immunosuppression in Ceará, Northeastern Brazil. The goal of this study was to determine the prevalence of Histoplasma infection in patients with HIV/AIDS living in Fortaleza, the capital of Ceará. Methods. Intradermal tests with histoplasmin (mycelial phase) were performed in 161 HIV patients with CD4 ≥ 350 cells/mm3. Evidence of recent illness was evaluated with immunodiffusion (ID) tests in 76 of these individuals. Results. A total of 11.8% of patients reacted to histoplasmin and 2.63% had ID test positive to Histoplasma. The presence of mango trees (Mangifera indica) in the patient neighborhood (OR = 2.870; 95% CI = 1.081-7.617; p = 0.040) and past activity involving soil (OR = 2.834; 95% CI = 1.045-7.687; p = 0.045) or visits to a farm (OR = 3.869; 95% CI = 1.189-12.591; p = 0.033) were significantly associated with Histoplasma infection. Conclusions. Patients with HIV living in Fortaleza have an expressive prevalence of infection with Histoplasma.
metadata.dc.type: Artigo de Periódico
Appears in Collections:PPGSP - Artigo publicado em revista científica

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