Efeito do treinamento de resistência de baixa Intensidade combinado a restrição parcial de fluxo sanguíneo na dor e função em Indivíduos com osteoartrite de joelho: protocolo para um ensaio controlado aleatorizado

Abstract

Osteoarthritis (OA) is a chronic degenerative condition that has clinical features such as pain and limited range of motion. Quadriceps weakness makes this joint more susceptible to wear and tear on the articular cartilage. In order to reduce joint pain during exercise, low to moderate intensity training is used, with the use of partial blood flow restriction (PBFR) as a new approach. Therefore, the aim of the study is to verify whether low-intensity resistance training in combination with PBFR is superior to low-intensity resistance training with PBFR-sham on pain and function in patients with knee OA. This is a randomized controlled trial, with two parallel groups of balanced and double-blind distribution. The primary outcome variables will be the Pain and Function Domains in the Knee Injury and Osteoarthritis Outcome Score (KOOS), and Knee pain intensity to be measured by the Numerical Pain Scale (END) in the eighth week of intervention. Other outcomes will be measured through functional tests, perception of global effect scale (EPEG), quadriceps strength assessment and medication use. There will be two weekly appointments for eight weeks. Knee extension and squat exercises will be performed with an intensity of 30% of 1RM. The hypothesis of this study is that the PBFR group presents superiority in pain and functional capacity outcomes compared to the PBFRsham group within an 8-week period. If effective, low-intensity exercise with PBFR will be a relevant treatment as it generates less pain during exercise.