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Campo DC | Valor | Idioma |
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dc.contributor.author | Morais, Talita Cavalcante | - |
dc.contributor.author | Lopes, Synara Cavalcante | - |
dc.contributor.author | Carvalho, Karine Maria Martins Bezerra | - |
dc.contributor.author | Arruda, Bruno Rodrigues | - |
dc.contributor.author | Souza, Francisco Thiago Correia de | - |
dc.contributor.author | Trevisan, Maria Teresa Salles | - |
dc.contributor.author | Rao, Vietla Satyanarayana | - |
dc.contributor.author | Santos, Flávia Almeida | - |
dc.date.accessioned | 2013-08-28T13:51:15Z | - |
dc.date.available | 2013-08-28T13:51:15Z | - |
dc.date.issued | 2012-07 | - |
dc.identifier.citation | MORAIS, T, C, et al. Mangiferin, a natural xanthone, accelerates gastrointestinal transit in mice involving cholinergic mechanism. World Journal of Gastroenterology, v. 18, n. 25, p. 3207-3214, jul. 2012. | pt_BR |
dc.identifier.issn | 1007-9327 (print) | - |
dc.identifier.issn | 2219-2840 (online) | - |
dc.identifier.uri | http://www.repositorio.ufc.br/handle/riufc/5705 | - |
dc.description.abstract | AIM: To investigate the effects of mangiferin on gas - trointestinal transit (GIT) in normal and constipated mice, together with the possible mechanism. METHODS: Intragastrically-administered charcoal mea was used to measure GIT in overnight starved Swiss mice. In the first experiments, mangiferin (3 mg/kg, 10 mg/kg, 30 mg/kg, and 100 mg/kg, po ) or tegaserod (1 mg/kg, ip ) were administered 30 min before the char - coal meal to study their effects on normal transit. In the second series, mangiferin (30 mg/kg) was tested on delayed GIT induced by several different pharma - cological agonists (morphine, clonidine, capsaicin) or antagonists (ondansetron, verapamil, and atropine) whereas in the third series, mangiferin (30 mg/kg, 100 mg/kg and 300 mg/kg) or tegaserod (1 mg/kg) were tested on 6 h fecal pellets outputted by freely fed mice. The ratio of wet to dry weight was calculated and used as a marker of fecal water content. | pt_BR |
dc.language.iso | en | pt_BR |
dc.publisher | World Journal of Gastroenterology | pt_BR |
dc.subject | Conteúdo Gatrointestinal | pt_BR |
dc.title | Mangiferin, a natural xanthone, accelerates gastrointestinal transit in mice involving cholinergic mechanism | pt_BR |
dc.type | Artigo de Periódico | pt_BR |
Aparece nas coleções: | DFIFA - Artigos publicados em revista científica |
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