Histoplasmose intestinal em pacientes transplantados renais: relato de casos e revisão da literatura

Abstract

Histoplasmosis is a systemic mycosis, affecting mainly immunocompromised patients with nonspecific clinical presentation. The presentation form is focal or widespread, the latter often fatal. The authors report two cases of intestinal histoplasmosis in renal transplant patients, with a low rate of clinical suspicion, who were diagnosed by lesion biopsy and showed a favorable outcome due to early treatment with liposomal amphoterecin b and maintenance with itraconazole. In the face of cases with varied and atypical clinical manifestations, this disease should be included in the diagnostic investigation of immunosuppressed individuals.