A vitamina D em pacientes críticos: uma revisão da literatura

Abstract

The vitamin D is liposoluble and have its actions influenced by numerous modulators, being indispensable for skeletal, neurological, immunological and cardiovascular health, with increasing attention to the fact that hypovitaminosis D increases the risk of hospital morbidity and mortality. This study aimed to review the recent literature, with studies published between 2009 and 2018 in important health databases, about vitamin D deficiency in critically ill patients and their possible consequences. The descriptors “critical care” and “vitamin D” were used. Eight articles were selected. There were higher rates of nutritional deficiency in intensive care patients than in healthy patients in different age groups, suggesting that hypovitaminosis would be associated with higher mortality rates. Vitamin D supplementation in these conditions has not yet been extensively studied, but there is a tendency to be beneficial, not bringing about adverse events. It is concluded that hypovitaminosis D is probably associated with worse clinical outcomes in critically ill patients, showing the need for large randomized multicenter studies to prove the need for its investigation and its correction.