Células-tronco dentárias na regeneração dos tecidos periodontais:uma revisão de literatura

Abstract

It can be indicated that periodontal tissues damaged by periodontal disease have a restricted regeneration efficiency. In this perspective, stem cell regenerative therapy has acquired space in the field of dentistry for the potential of these self-renewing cells, and after division, can give rise to cells with differentiation capacity, in order to favor the formation of new structures periodontal such as cementum, bone and periodontal ligament fibers. The aim of this study is to carry out a literature review in order to evaluate the potential of dental stem cells in the process of periodontal tissue regeneration. As methodology, a data search was performed at the base “PubMed”, “Scielo” e “Lilacs” using the fundamentals “Stem cell”, “Periodontal disease” and “Regeneration” without limitations between the languages sought. 408 articles were found which, after the reading and selection process, were used 11 articles that met the inclusion criteria. It was used as an exclusion factor for articles that ran away from the highlighted topic and articles from literature reviews. In this way, studies were found with promising results in the neoformation of the tissue periodontal structures, suggesting a potential of the dental stem cell in the process of periodontal regeneration. However, further multicenter randomized controlled trials with increased sample size are required to evaluate the applicability of cell therapy to dental stem cells.