Dental status, salivary flow, and sociodemographic aspects in Sheehan Syndrome patients

Abstract

Background: Sheehan’s syndrome (SS) is one of the leading causes of hypopituitarism in developing countries. It occurs after postpartum necrosis of the pituitary gland, and it is considered a significant public health problem. This paper, apparently unpublished, aimed to perform an analysis on oral aspects in patients with SS. Material and Methods: A cross-sectional study was performed with 23 women diagnosed with SS at the Division of Endocrinology and Diabetes (Walter Cantídio University Hospital, Fortaleza, Brazil). Results: Data on sociodemographic, dental and salivary flow aspects were collected through a clinical approach and a panoramic radiograph request. The mean age was 64 ± 11.5 years old, with the sample consisting mainly of married women (56.5%), socioeconomic class C2 or D / E (78.2%) and years of education up to 8 years (69.5%). The presence of horizontal bone loss ( p <0.001) and bilateral pneumatization of the maxillary sinus ( p =0.015) were significant data. The mean number of absent teeth considering all subjects was 23.17±9.7, being statistically significant ( p <0.001). In relation to age, the mean number of missing teeth was higher in individuals over 65 years old ( p =0.048). Reduced salivary flow was observed in 78.3% of the patients. In a bivariate analysis, considering the outcome variables “missing teeth” and “reduced salivary flow”, it was observed that economic class ( p <0.001), family income (0.037) and maxillary sinus pneumatization (0.032) were statistically significant. Conclusions: In brief, patients with SS showed severe teeth loss, reduced salivary flow, and low educational status. This study addressed important aspects regarding oral findings in SS and highlighted the importance of researches in oral medicine.