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dc.contributor.authorGomes, Sara L. S.-
dc.contributor.authorMilitão, Gardenia C. G.-
dc.contributor.authorCosta, Arinice M.-
dc.contributor.authorPessoa, Cláudia Ó.-
dc.contributor.authorCosta-Lotufo, Letícia V.-
dc.contributor.authorTorres-Santos, Eduardo C.-
dc.contributor.authorCosta, Paulo R. R.-
dc.contributor.authorSilva, Alcides J. M. da-
dc.contributor.authorCunha-Junior, Edézio F.-
dc.date.accessioned2017-11-08T14:22:35Z-
dc.date.available2017-11-08T14:22:35Z-
dc.date.issued2017-
dc.identifier.citationGOMES, S. L. S. et al. Suzuki-Miyaura coupling between 3-Iodolawsone and Arylboronic acids. Synthesis of Lapachol analogues with antineoplastic and antileishmanial activities. Journal of the Brazilian Chemical Society, São Paulo, v. 28, n. 8, p. 1573-1584, 2017.pt_BR
dc.identifier.issn0103-5053-
dc.identifier.urihttp://www.repositorio.ufc.br/handle/riufc/27266-
dc.description.abstractA series of 2-hydroxy-3-arylnaphthalene-1,4-diones (3-aryllawsones) were synthesized by Suzuki-Miyaura cross coupling reaction of 3-iodolawsone with arylboronic acids/esters. The hydroxylated resulting products were transformed into their corresponding N , N -diethyl carbamates. The antineoplastic and antileishmanial activities of the compounds were evaluated and compared with lapachol and its carbamate, providing promising results.pt_BR
dc.language.isoenpt_BR
dc.publisherJournal of the Brazilian Chemical Societypt_BR
dc.subjectQuinonespt_BR
dc.subjectQuinonaspt_BR
dc.subjectLevopropoxifenopt_BR
dc.titleSuzuki-Miyaura coupling between 3-Iodolawsone and arylboronic acids. Synthesis of lapachol analogues with antineoplastic and antileishmanial activitiespt_BR
dc.typeArtigo de Periódicopt_BR
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