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Title in Portuguese: Vitamin D levels in juvenile idiopathic arthritis from an equatorial region
Author: Studart, Sâmia Araújo de Sousa
Leite, Ana Caroline Rocha de Melo
Marinho, Aryana Lushese Lima Feitosa
Pinto, Ana Carolina Matias Dinelly
Rabelo Júnior, Carlos Nobre
Nunes, Rodolfo de Melo
Rocha, Hermano Alexandre Lima
Rocha, Francisco Airton Castro
Keywords: Artrite
Vitamina D
Issue Date: Oct-2015
Publisher: Rheumatology International
Citation: STUDART, S. A. S. et al. Vitamin D levels in juvenile idiopathic arthritis from an equatorial region. Rheumatology International, Berlin, v. 35, n. 10, p. 1717–23, out. 2015.
Abstract: We aimed to describe the serum levels of 25-hydroxyvitamin D (25OHD) in juvenile idiopathic arthritis (JIA) patients living in a low-latitude (3°43′S) region. Fifty JIA patients, 31 (62 %) female, seen between May 2012 and April 2013 in the northeast of Brazil had clinical data and serum collected for determination of 25OHD and parathyroid hormone (PTH) using a chemiluminescent ELISA; 20 age- and sex-matched controls were used for comparison. Mean age was 13.4 ± 4 years. Twenty-five (50 %), 15 (30 %), 4 (8 %), 4 (8 %), and 2 (4 %) patients were of the polyarticular, oligoarticular, systemic, enthesitis-related, and undifferentiated categories, respectively. Mean 25OHD was 31.6 ± 10 and 30.4 ± 5.7 ng/mL in patients and controls (P > 0.05), respectively; PTH was normal in JIA and controls; 25OHD was similar regardless of JIA category, disease activity, or severity measured by JADAS-27, CHAQ, or presence of joint deformities. Twenty-six (52 %), 20 (40 %), and 4 (8 %) patients were considered to have optimal, sufficient, and deficient 25OHD levels, respectively, whereas 11 (52 %) and 10 (48 %) controls had optimal and sufficient 25OHD. Ethnicity, body mass index, seasonal variation, and use of steroids did not influence 25OHD levels. This is the first study on 25OHD levels in JIA patients living in a low-latitude region, showing the lowest prevalence of vitamin D deficiency ever reported. Serum 25OHD was similar in JIA and controls and did not vary regardless of JIA category or severity.
metadata.dc.type: Artigo de Periódico
ISSN: 0172-8172 (Print)
1437-160X (Online)
Appears in Collections:PPGSP - Artigo publicado em revista científica

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