Uso de marcadores moleculares na depressão : prospecção tecnológica

Abstract

Depression is the most common psychiatric disorder, constituting a condition that includes psychological symptoms, behavioral and physical. Knowledge about the presence or absence of mutations in genes involved in the metabolism of antidepressants can provide important information to assist in handling and choosing dosages of the drugs used for the treatment of depression. The present study aimed to conduct a survey on the research already developed and patented results on the use of molecular markers in depression. Prospecting was carried out based on the patent applications filed in 4 analyzed databases, namely, National Institute of Industrial Property (INPI) of Brazil, the European Patent Office (EPO), United States Patent and Trademark Office (USPTO) and World Intellectual Property Organization (WIPO). After research it was found a small number of patents, only 7 found in the databases analyzed, it is classified in three different classes C12Q, A61K and A61B. However the clinical use of molecular markers in depression, still requires substantial investment in obtaining data from IRAM studies provide important information about this disease.