Use este identificador para citar ou linkar para este item: http://repositorio.ufc.br/handle/riufc/9240
Tipo: Artigo de Periódico
Título: Antimicrobial effect of Lippia sidoides and Thymol on Enterococcus faecalis biofilm of the bacterium isolated from root canals
Autor(es): Veras, H. N. H.
Rodrigues, F. F. G.
Botelho, Marco Antonio
Menezes, Irwin Rose Alencar de
Coutinho, Henrique Douglas Melo
Costa, José Galberto Martins da
Palavras-chave: Timol;Enterococcus
Data do documento: 2014
Instituição/Editor/Publicador: The Scientific World Journal
Citação: VERAS, H. N. H. et al. Antimicrobial Effect of Lippia sidoides and Thymol on Enterococcus faecalis biofilm of the bacterium isolated from root canals. The Scientific World Journal, v. 2014, p. 1-5, 2014.
Abstract: The species Lippia sidoides Cham. (Verbenaceae) is utilized in popular medicine as a local antiseptic on the skin and mucosal tissues. Enterococcus faecalis is the bacterium isolated from root canals of teeth with persistent periapical lesions and has the ability to form biofilm, where it is responsible for the failure of endodontic treatments. Essential oil of L. sidoides (EOLS) and its major component, thymol, were evaluated for reducing the CFU in biofilms of E. faecalis in vitro. The essential oil was obtained by hydrodistillation and examined with respect to the chemical composition, by gas chromatography-mass spectrometry (GCMS). The GC-MS analysis has led to the identification of thymol (84.9%) and p-cymene (5.33%). EOLS and thymol reduced CFU in biofilms of E. faecalis in vitro (time of maturation, 72 h), with an exposure time of 30 and 60 min at concentrations of 2.5 and 10%. There was no statistical difference in effect between EOLS and thymol, demonstrating that this phenolic monoterpene was the possible compound responsible for the antimicrobial activity of EOLS.This study provides a basis for the possible utilization of EOLS as an adjuvant in the treatment of root canals that show colonization by E. faecalis.
URI: http://www.repositorio.ufc.br/handle/riufc/9240
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