Please use this identifier to cite or link to this item: http://www.repositorio.ufc.br/handle/riufc/8552
Title in Portuguese: In vitro activities of amoxicillin-clavulanate, doxycycline, ceftazidime, imipenem, and trimethoprim-sulfamethoxazole against biofilm of Brazilian strains of Burkholderia pseudomallei
Author: Bandeira, Tereza de Jesus Pinheiro Gomes
Moreira, Camila Alencar
Brilhante, Raimunda Sâmia Nogueira
Castelo-Branco, Débora de Souza Collares Maia
Araújo Neto, Manoel Paiva de
Cordeiro, Rossana de Aguiar
Rodrigues, Terezinha de Jesus Santos
Rocha, Marcos Fábio Gadelha
Sidrim, José Júlio Costa
Keywords: Amoxicilina
Doxiciclina
Issue Date: Nov-2013
Publisher: Antimicrobial agents and chemotherapy
Citation: BANDEIRA, T. J. P. G. et al. In vitro activities of amoxicillin-clavulanate, doxycycline, ceftazidime, imipenem, and trimethoprim-sulfamethoxazole against biofilm of brazilian strains of burkholderia pseudomallei. Antimicrobial Agents and Chemotherapy, Bethesda, v. 57, n. 11, p. 5771-3, nov. 2013.
Abstract: This study aimed at investigating the in vitro activities of amoxicillin-clavulanate, doxycycline, ceftazidime, imipenem, and trimethoprim- sulfamethoxazole against Burkholderia pseudomallei in planktonic and biofilm forms, through broth microdilution and resazurin-based viability staining, respectively. In planktonic growth, the strains were susceptible to the drugs, while in biofilm growth, significantly higher antimicrobial concentrations were required, especially for ceftazidime and imipenem, surpassing the resistance breakpoints. These results highlight the importance of the routine evaluation of biofilm antimicrobial susceptibility.
URI: http://www.repositorio.ufc.br/handle/riufc/8552
ISSN: 0066-4804 Impresso
Appears in Collections:DMC - Artigos publicados em revistas científicas

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