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Title in Portuguese: Oxygen metabolism in oral câncer : HIF and GLUTs (review)
Author: Pereira, Karuza Maria Alves
Chaves, Filipe Nobre
Viana, Thales Salles Angelim
Carvalho, Francisco Samuel Rodrigues
Costa, Fábio Wildson Gurgel
Alves, Ana Paula Negreiros Nunes
Sousa, Fabrício Bitu
Keywords: Oxigênio
Neoplasias Bucais
Issue Date: Aug-2013
Publisher: Oncology Letters
Citation: PEREIRA, K. M. A. et al. Oxygen metabolism in oral câncer : HIF and GLUTs (review). Oncology Letters, Athens, v. 6, n. 2, p. 311-316, ago. 2013.
Abstract: Oral cancer is a significant cause of morbidity and mortality, and has a poor prognosis. This has encouraged additional studies into factors that may affect the development of this disease. The biological behavior of malignant neoplasms is complex. Studies have investigated the energy metabolism of tumor cells, in an endeavor to elucidate the tumor biology. The identification of molecular signatures and mechanisms, in order to understand tumor progression, may facilitate the identification of novel predictive and prognostic markers. Pathways that influence tumor progression, such as those involving hypoxia‑inducible factor (HIF) and glucose transporter (GLUT) proteins, have been the targets of recent studies.
metadata.dc.type: Artigo de Periódico
ISSN: 1792-1074 (Print)
1792-1082 (Electronic)
Appears in Collections:DCOD - Artigos publicados em revistas científicas

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