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Title in Portuguese: GABAergic transmission and modulation of anxiety: a review on molecular aspects
Author: Gomes, Francisco Isaac Fernandes
Aragão, Maria Gerusa Brito
Bezerra, Mirna Marques
Chaves, Hellíada Vasconcelos
Keywords: Ansiedade
Issue Date: 2019
Publisher: Brazilian Journal of Biological Sciences
Citation: GOMES, Francisco Isaac Fernandes et al. GABAergic transmission and modulation of anxiety: a review on molecular aspects. Braz. J. Biol. Sci., v. 6, n. 12, p. 9-16, 2019.
Abstract: Stress responses activate protective mechanisms to achieve homeostasis, but they can be detrimental when such responses become maladaptive. Anxiety relates to risk assessment of a potential threat and involves uncertainty regarding the anticipation of a threatening situation and it dampers quality of life. Gamma-Aminobutyric Acid (GABA) is the major inhibitory system in the central nervous system and plays a key role in the regulation of neuronal transmission in the brain, affecting many physiological and psychological processes. This mini-review aims to summarize key points concerned with the GABAergic transmission and basic aspects related to the GABAergic system in anxiety.
metadata.dc.type: Artigo de Periódico
ISSN: 2358-2731
Appears in Collections:DCOD - Artigos publicados em revistas científicas

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