Use este identificador para citar ou linkar para este item: http://repositorio.ufc.br/handle/riufc/25527
Tipo: Artigo de Periódico
Título: Challenges for conducting blood collection and biochemical analysis in a large multicenter school-based study with adolescents: lessons from ERICA in Brazil
Título em inglês: Challenges for conducting blood collection and biochemical analysis in a large multicenter school-based study with adolescents: lessons from ERICA in Brazil
Autor(es): Cureau, Felipe Vogt
Bloch, Katia Vergetti
Henz, Aline
Schaan, Camila W.
Klein, Carlos Henrique
Oliveira, Cecília Lacroix de
Leon, Elisa Brosina de
Abreu, Gabriela de Azevedo
Telo, Gabriela Heiden
Dias, Glauber Monteiro
Carvalho, Kênia Mara Baiocchi de
Barufaldi, Laura Augusta
Kuschnir, Maria Cristina Caetano
Szklo, Moyses
Montenegro Jr., Renan
Silva, Thiago Luiz Nogueira da
Ekelund, Ulf
Schaan, Beatriz D.
Giannini, Denise Tavares
Palavras-chave: Blood Specimen Collection;Clinical Laboratory Techniques;Cardiovascular Diseases
Data do documento: 2017
Instituição/Editor/Publicador: Cadernos de Saúde Publica
Citação: CUREAU, F. V. et al. Challenges for conducting blood collection and biochemical analysis in a large multicenter school-based study with adolescents: lessons from ERICA in Brazil. Cadernos de Saúde Publica, v. 33, p. 1, 2017.
Abstract: The Study of Cardiovascular Risk in Adolescents (ERICA) is a pioneering study that aimed to assess the prevalence of cardiovascular risk factors, including metabolic syndrome components in Brazilian adolescents. This study aims to describe the methodological aspects related to blood collection as well as to report pertaining results of the preparation, transport, storage, and exams in ERICA. Exams in ERICA were performed in a single laboratory and blood samples were collected in schools in a standardized manner. Logistics involved air transportation of samples to the reference laboratory with controlled temperature since sample collection. The serum was stored in local biorepositories in four centers to be used in future analyses. During the study, 284,247 exams were performed and rate of participation in exams was 56.2%, thus involving 40,732 adolescents. From the total, 92.6% of the samples reached the reference laboratory maintaining the temperature between 0-10°C. No clinical significant changes in results due to temperature changes were identified. External quality control recorded satisfactory results in 98.7% of the evaluations. Four biorepositories with samples of 7,785 adolescents were created. Thus, we can consider that the logistics adopted in ERICA was fairly successful and description of this as well as the difficulties experienced in Brazil can inform and facilitate the planning of future studies, especially in developing countries.
URI: http://www.repositorio.ufc.br/handle/riufc/25527
ISSN: 0102-311X
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